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Anxiety disorders may be caused by environmental factors, medical factors, genetics, brain chemistry, substance abuse, or a combination of these. It is most commonly triggered by the stress in our lives.

Usually anxiety is a response to outside forces, but it is possible that we make ourselves anxious with "negative self-talk" - a habit of always telling ourselves the worst will happen.

Anxiety caused by environmental and external factors

Environmental factors that are known to cause several types of anxiety include:

- Trauma from events such as abuse, victimization, or the death of a loved one

- Stress in a personal relationship, marriage, friendship, and divorce

- Stress at work

- Stress from school

- Stress about finances and money

- Stress from a natural disaster

- Lack of oxygen in high altitude areas

Anxiety caused by medical factors

Anxiety is associated with medical factors such as anemia, asthma, infections, and several heart conditions. Some medically-related causes of anxiety include:

- Stress from a serious medical illness

- Side effects of medication

- Symptoms of a medical illness

- Lack of oxygen from emphysema, or pulmonary embolism (a blood clot in the lung)

Anxiety caused by substance use and abuse

It is estimated that about half of patients who utilize mental health services for anxiety disorders such as GAD, panic disorder, or social phobia are doing so because of alcohol or benzodiazepine dependence. More generally, anxiety is also know to result from:

- Intoxication from an illicit drug, such as cocaine or amphetamines

- Withdrawal from an illicit drug, such as heroin, or from prescription drugs like Vicodin, benzodiazepines, or barbiturates

Anxiety caused by genetics

It has been suggested by some researchers that a family history of anxiety increases the likelihood that a person will develop it. That is, some people may have a genetic predisposition that gives them a greater chance of suffering from anxiety disorders.

Anxiety caused by brain chemistry

Research has shown that people with abnormal levels of certain neurotransmitters in the brain are more likely to suffer from generalized anxiety disorder. When neurotransmitters are not working properly, the brain's internal communication network breaks down, and the brain may react in an inappropriate way in some situations. This can lead to anxiety.

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