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It is the ability to recognize danger leading to an urge to confront it or flee from it. Fear can also be an instant reaction to something presently happening.

Fear is a chain reaction in the brain that starts with a stressful stimulus and ends with the release of chemicals that cause a racing heart, fast breathing and energized muscles, among other things, also known as the fight-or-flight response.

There are certain areas of the brain at least peripherally involved in fear.

Thalamus
Sensory cortex
Hippocampus
Amygdala
Hypothalamus
Amygdala


The amygdala is an area of our brain with almond-shaped and receives a large amount of information in our environment, for example, smells, sights, sounds. The signals from the amygdala reach the hypothalamus, the area where corticotropic releasing hormone (HCT), which in turn is responsible for the release of cortisol (stress hormone).

Cortisol is the substance responsible for leading the fight or flight through connections with our metabolism, since it directly influences the amount of glucose you should get the muscles.

When the amygdala oxytocin dominates the person is calmer in situations of danger, while if more vasopressin increases anxiety, uncertainty and, ultimately, fear grips us and our body prepares for fight or flight.

There is a particular dysfunction involving an abnormal deposit of calcium in the amygdala that produces an impairment of those nuclei to sense and experience fear.


How to overcome fear?

According to current research work on animals like mice scientists proved that by deleting cannabinoid receptor type 1 (CB1) results in a loss of ability to regulate fear.

CB1 receptors are found primarily in the brain, to be specific in the basal ganglia and in the limbic system, including the hippocampus. They are also found in the cerebellum and in both male and female reproductive systems

Cannabinoids are a class of diverse chemical compounds that activate cannabinoid receptors. These include the endocannabinoids (produced naturally in the body by humans and animals), the phytocannabinoids (found in cannabis and some other plants), and synthetic cannabinoids (produced chemically by humans).

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